Nonylphenol is toxic to aquatic organisms demonstrated, in part, through recent national criteria established by the EPA (AWQC– Nonylphenol 2007( EPA822R05005)). The need to develop national criteria was based both on concerns of NP toxicity and its presence in surface waters throughout the nation. The

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NONYL PHENOL ETHOXYLATED Safety Data Sheet www.lobachemie.com 09/04/2015 6/10 Aspiration hazard : Not classified Potential adverse human health effects and symptoms: Harmful if swallowed. SECTION 12: Ecological information 12.1. Toxicity Ecology - water : Very toxic to aquatic life with long lasting effects. 12.2. Persistence and degradability

Precautionary statements tion of NPEs occurs through the loss of ethoxylate (EO) groups, resulting in compounds that are more toxic, estrogenic, and environmentally persistent than the parent compounds (Environment Canada 2000). Primary biodeg-radation of NPEs in aquatic systems is fast, but the resul-tant products, nonylphenol monoethoxylate (NP1EO), Nonylphenol and its ethoxylates. • EC (2001), EU-RAR on 4-nonylphenol (branched) and Nonylphenol. Given the few available risk assessments on NP and its parent compounds it was not possible to compare the integrated assessment with one ecological risk assessment report with one human health risk assessment report. Nonylphenol is highly toxic to aquatic organisms and has been found in natural waters.

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One of these environmental Production. Nonoxynols are produced by ethoxylation of alkylphenols and vary in the number of repeating ethoxy (oxy-1,2-ethanediyl) groups resulting in Nonoxynol-4, Nonoxynol-7, Nonoxynol-9, Nonoxynol-14, Nonoxynol-15, Nonoxynol-18, Nonoxynol-40, Nonoxynol-30 and Nonoxynol-50. Nonylphenol ethoxylates in imported textiles iii Abstract Nonylphenol is a priority hazardous substance under the Water Framework Directive (WFD) due to its potential impact upon the aquatic environment. Water quality monitoring continues to detect nonylphenol (NP) and nonylphenol ethoxylate (NPE) in waterways across the UK. NPEs are degraded to shorter chain nonylphenol ethoxylates as well as shorter nonylphenol ethoxycarboxylates under aerobic condition, before being biodegraded to nonylphenol. Shorter ethoxylate chain alkylphenols have greater toxicity than longer ones. CCME describes Toxic Equivalent Factors from Environment Canada for NPnEO (1≤n≤8) Nonylphenol is toxic to aquatic organisms demonstrated, in part, through recent national criteria established by the EPA (AWQC– Nonylphenol 2007( EPA822R05005)).

Intergenerational toxicity of nonylphenol ethoxylate (NP-9) in Caenorhabditis elegans. De la Parra-Guerra A(1), Stürzenbaum S(2), Olivero-Verbel J(3). Author information: (1)Environmental and Computational Chemistry Group, University of Cartagena, Cartagena, Colombia.

nonylphenol mono- and diethoxylates (NP1EO and NP2EO), mono- and di-nonylphenoxy carboxylic acids (NP1EC and NP2EC) have also been considered in this report. Acute toxicity (oral), Category 4 H302 Skin corrosion/irritation, Category 1B H314 Reproductive toxicity, Category 2 H361fd Hazardous to the aquatic environment — Chronic Hazard, Category 1 H410 Full text of classification categories and H statements : see section 16 Classification according to Directive 67/548/EEC or 1999/45/EC Repr.Cat.3; R62 Request PDF | Toxicity of nonylphenol and nonylphenol ethoxylate on Caenorhabditis elegans | Among the most used chemicals in the world are nonionic surfactants. One of these environmental Nonylphenol Ethoxylates (NPE) in All-Purpose Cleaners LAE linear alcohol ethoxylate LAS linear alkylbenzene sulfonate LC 50 median lethal concentration LCI Life cycle inventory LD 50 R reproductive toxicity REACH Registration, Evaluation, Authorisation and Restriction of Chemical Substances Currently, the aquatic toxicity testing EPA is considering would focus on testing NP and the short-chain NPEs, i.e., nonylphenol with one or two ethoxylates groups attached. EPA is soliciting comment on the most appropriate selection and purity of NP and NPEs to test.

alkyl chain, and a water soluble chain of 1-100 ethoxylate groups (1EO-100EO) [7]. The mostly used APEs, nonylphenol ethoxylates (NPEs) has an alkyl chain (C9H19, usually branched) and a chain of 9-10 ethoxylate groups (see Fig.1) [9]. With decreasing length of the ethoxylate chain, bioaccumulation and toxicity of APEs increases [10].

Nonylphenol ethoxylate toxicity

Breakdown of all 4512 C&L notifications submitted to ECHA The effects of nonylphenol ethoxylates and nonylphenol in the environment have been extremely controversial. Concerns first emerged in 1983–84 when Giger and co-workers from Switzerland established that nonylphenol ethoxylates and products of degradation were more toxic to aquatic life than their precursors (Giger et al., 1984). Intergenerational toxicity of nonylphenol ethoxylate (NP-9) in Caenorhabditis elegans. De la Parra-Guerra A(1), Stürzenbaum S(2), Olivero-Verbel J(3). Author information: (1)Environmental and Computational Chemistry Group, University of Cartagena, Cartagena, Colombia. Nonyl-phenol ethoxylates have much narrower homologue distributions than alcohol ethoxylates (ICI datasheet for Synperonic NP surfactants).

Nonylphenol ethoxylate toxicity

- Ingested poisons NOTE: Solvents containing NPE (nonyl phenol ethoxylate), such as scintillation liquids like  B E Fatty alcohol ethoxylates nonylphenol- or risk => A = Allergy, C = Cancer, T = Toxic, E = Environmentally hazardous, N = Neurotoxic,. (1992) Determination of alkylphenol ethoxylates and their acetic acid (1984) 4-nonylphenol in sewage sludge: Accumulation of toxic metabolites from nonionic  av A Julander · Citerat av 2 — Other substances that are highly toxic at skin exposure are substances and preparations (nonylphenol, nonylphenol ethoxylate and cement) (Text with. Engelska.
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Nonylphenol ethoxylate toxicity

ing mixtures (about 34,600 tons if calculated in terms of 100 % alkylphenol ethoxylate according to the survey by Japan Surfactant Industry Association). Of this production, about 85 % was ac-counted for by nonylphenol ethoxylates, and the remainder by octylphenol ethoxylates, etc.11) 4-nonylphenol (4-NP) is an estrogenic endocrine active chemical that is present in detergents and is known to contaminate food and drinking water.The aim of the present study was to evaluate whether 4-NP crosses the human placenta and if so, to what extent. Nonylphenol was found to induce vitellogenin at 20.3 (μg/L and completely inhibit testicular growth at 54.3 (μg/L. Octylphenol was found to induce vitellogenin at 4.8 (μg/L but did not affect gonadal size at concentrations up to 43.9 (μg/L (the highest concentration tested) when compared with controls.

From data obtained by Environment Canada, an estimated 18,000 tonnes of NP and NPEs were used in Canada in 1998. Since they are highly persistent and hydrophobic, they accumulate mostly on sludge.In this study using Anaerobic Toxicity Assay (ATA) tests, the toxicity of a model nonylphenol compound, nonylphenol diethoxylate (NP2EO), for anaerobic digestion of sludge was determined.
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Nonylphenol ethoxylate toxicity aq components vasteras
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2004. Toxicity of Nonylphenol Ethoxylate. Metabolites. Many countries, large corporations and scien- tific entities have classified NPE metabolites as toxic.

NP has also been shown to exhibit estrogenic properties in in vitro and in vivo assays. NP’s main use is in the manufacture of NPEs.


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confusion matrix

Nonylphenol and nonylphenol ethoxylates have been shown to bind to NPEs degrade to more toxic chemicals, including NP, which often partitions to 

880 million pounds (4 mio metric tonnes) of alkyl phenol ethoxylates are used annually throughout the world. 80-85% are sold as nonylphenol ethoxylate (NPE), over 15% as octylphenol ethoxylate, and 1% each as Toxic substances list: nonylphenol and its ethoxylates. Nonylphenol and its ethoxylates (NP and NPEs) have been used for more than 40 years as detergents, emulsifiers, wetting agents and dispersing agents. From data obtained by Environment Canada, an estimated 18,000 tonnes of NP and NPEs were used in Canada in 1998.

29 Mar 2021 NP is produced from the environmental degradation of nonylphenol ethoxylates, which are toxic nonylphenol metabolites [1, 2]. In addition, NP 

NP has also been shown to exhibit estrogenic properties in in vitro and in vivo assays.

4-Nonylphenol, branched and linear, ethoxylated. OSH. Occupational safety and health. PBT. Persistent, bioaccumulative and toxic. NP is persistent in the aquatic environment, moderately bioaccumulative, and extremely toxic to aquatic organisms. NP has also been shown to exhibit estrogenic properties in in vitro and in vivo assays. NP’s main use is in the manufacture of NPEs.